|
Symbol Name ID |
Zic2
zinc finger protein of the cerebellum 2 MGI:106679 |
| Darker colors indicate more annotations |
| Human Phenotypes | Dandy-Walker malformation |
Microcephaly |
Encephalocele |
Anosmia |
Hyposmia |
Anterior hypopituitarism |
Panhypopituitarism |
Spasticity |
Abnormal nervous system morphology |
Lateral ventricle dilatation |
Hydrocephalus |
Aplasia/Hypoplasia of the corpus callosum |
Aplasia/Hypoplasia of the cerebellum |
Holoprosencephaly |
Alobar holoprosencephaly |
Lobar holoprosencephaly |
Semilobar holoprosencephaly |
Syntelencephaly |
Spinal dysraphism |
Spinal cord tumor |
Abnormality of neuronal migration |
Chorea |
Cognitive impairment |
Intellectual disability |
Dystonia |
Global developmental delay |
Seizure |
| Disease(s) Associated with ZIC2 | |||||||||||||||||||||||||||
| holoprosencephaly | |||||||||||||||||||||||||||
| holoprosencephaly 5 |
| Mouse Phenotypes | abnormal neural plate morphology |
abnormal neural tube morphology |
abnormal enteric neural crest cell morphology |
decreased neural crest cell number |
delayed caudal neuropore closure |
incomplete rostral neuropore closure |
spina bifida |
decreased rhombomere 3 size |
decreased rhombomere 5 size |
abnormal roof plate morphology |
abnormal enteric nervous system morphology |
abnormal enteric neuron morphology |
abnormal brain development |
abnormal forebrain development |
abnormal telencephalon development |
holoprosencephaly |
alobar holoprosencephaly |
decreased brain size |
enlarged lateral ventricles |
decreased corpus callosum size |
abnormal amygdala morphology |
abnormal cerebral hemisphere morphology |
abnormal cerebral cortex morphology |
thin cerebral cortex |
abnormal olfactory bulb morphology |
abnormal nervous system development |
anencephaly |
exencephaly |
abnormal neurite morphology |
decreased neuron number |
abnormal dorsal root ganglion morphology |
abnormal spinal cord dorsal horn morphology |
decreased prepulse inhibition |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
| Zic2iso/Zic2iso | ||||||||||||||||||||||||||||||||||
| Zic2Ku/Zic2Ku | ||||||||||||||||||||||||||||||||||
| Zic2m1Nisw/Zic2m1Nisw | ||||||||||||||||||||||||||||||||||
| Zic2tm1Jaru/Zic2tm1Jaru | ||||||||||||||||||||||||||||||||||
| Zic2Ku/Zic2+ | ||||||||||||||||||||||||||||||||||
| Zic2tm1Jaru/Zic2+ | ||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools